Q-omics provides the consensus-scored RPL36AP40 profile across patient tissues and cancer cell-line models. RPL36AP40 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, RPL36AP40 is differentially expressed in 9, with the highest sampling consensus in KIRC. Additionally, RPL36AP40 RNA expression shows 5,908 significant protein co-abundance associations, with the highest sampling consensus in OV. Together, these results highlight KIRP, KIRC, and OV as cancer lineages where RPL36AP40 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPL36AP40 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPL36AP40 survival associations across molecular data types. RPL36AP40 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPL36AP40 RNA expression–survival associations across cancer types. High RPL36AP40 expression shows unfavorable associations in KIRP, UCEC, CHOL and SKCM, but favorable associations in CESC and MESO. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRP as the clearest survival context for RPL36AP40 RNA expression.
This table summarizes RPL36AP40 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for RPL36AP40. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPL36AP40 shows lower tumor expression in KIRC, KICH, KIRP and BRCA and higher tumor expression in LUAD and LIHC. The KIRC box plot shows higher RPL36AP40 RNA expression in normal versus tumor tissue (log2 FC = −0.415, t-test p < 0.001).
This table shows molecular features associated with RPL36AP40 in patient tissues and cancer cell lines. In patient samples, RPL36AP40 shows the broadest associations at the RNA and protein expression levels, with OV recurring as the lineage with the largest associated feature set.
