RPL36AP14

Across TCGA pan-cancer cohorts, RPL36AP14 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPL36AP14’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RPL36AP14 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL36AP14 is over-expressed in tumor, although a few such as BRCA and LUAD show the opposite, repressed pattern.

BRCA, LUAD, and LUSC are the cancer types where RPL36AP14 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL36AP14 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	−0.037	.002	4	view →
LUAD	All	III,IV	−0.098	.042	2	view →
LUSC	All	All	−0.028	.012	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RPL36AP14–BRCA

Open the BRCA breakdown →