RPL36A-HNRNPH2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPL36A-HNRNPH2 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL36A-HNRNPH2-associated genes across cancer lineages are NIPA2P3, PRAMEF13, and SNORD114-1. Each is linked with RPL36A-HNRNPH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL36A-HNRNPH2-to-partner and partner-to-RPL36A-HNRNPH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NIPA2P3 grouped by RPL36A-HNRNPH2-low versus RPL36A-HNRNPH2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL36A-HNRNPH2→partner) and Y-score (partner→RPL36A-HNRNPH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNIPA2P3 →+0.138+6.582<.001.00131
UCECPRAMEF13 →+0.086+6.453<.001.00131
UCECSNORD114-1 →+0.754+5.299.008.00631
UCECRN7SKP113 →+0.268+5.621<.001.00431
UCECRNU6-47P →+0.594+5.420<.001.00531
UCECRNU6-1039P →+0.599+5.694<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

NIPA2P3 by RPL36A-HNRNPH2 expression — UCEC

Box plot of NIPA2P3 in RPL36A-HNRNPH2-low vs RPL36A-HNRNPH2-high samples in UCEC.

Explore this box plot interactively →

Exploration