RPL36A-HNRNPH2

Across TCGA pan-cancer cohorts, RPL36A-HNRNPH2 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RPL36A-HNRNPH2 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RPL36A-HNRNPH2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL36A-HNRNPH2 expression acts as an unfavorable survival marker, although some lineages such as MESO and LGG show a favorable association.

KIRP, MESO, and UCEC are the cancer types where RPL36A-HNRNPH2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	IV	0.035	0.433	.004	27	view →
MESO	OS	Tertile	IV	0.918	0.429	.007	26	view →
UCEC	DFS	Median	All	0.781	0.873	.002	22	view →
LGG	DFS	Median	All	0.827	0.667	.006	19	view →
ACC	DFS	Median	III,IV	0.558	0.135	.007	15	view →
LUAD	OS	Tertile	All	0.183	0.437	.005	14	view →
CESC	DFS	Tertile	All	0.714	0.410	.011	14	view →
STAD	OS	Quartile	II,III,IV	0.741	0.554	.014	12	view →
SARC	OS	Quartile	All	0.615	0.817	.002	12	view →
KIRC	DFS	Median	IV	0.526	0.685	.036	7	view →
BRCA	OS	Median	All	0.972	0.953	.024	7	view →
THCA	DFS	Median	IV	0.498	1.000	.012	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RPL36A-HNRNPH2–KIRP (DFS)

Open the KIRP breakdown →