RPL32

Across TCGA patient cohorts, RPL32 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL32-associated genes across cancer lineages are RNU1-117P, RNU6-993P, and MIR668. Each is linked with RPL32 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL32-to-partner and partner-to-RPL32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-117P grouped by RPL32-low versus RPL32-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL32→partner) and Y-score (partner→RPL32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RNU1-117P →	+0.405	+5.857	<.001	.002	3	2
GBM	RNU6-993P →	+0.582	+4.969	<.001	.009	3	1
SKCM	MIR668 →	+0.308	+7.816	<.001	.008	3	1
UCEC	OR51A7 →	+0.136	+3.021	.001	.006	3	1
HNSC	RNU6-458P →	+0.343	+7.954	<.001	.008	3	1
UCEC	FGF21 →	+0.621	+3.568	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

RNU1-117P by RPL32 expression — GBM

Explore this box plot interactively →