RPL32

Across TCGA pan-cancer cohorts, RPL32 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated RPL32 data layer compared with 1 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in uveal melanoma (UVM), where higher RPL32 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RPL32 expression acts as an unfavorable survival marker, although some lineages such as UVM and LGG show a favorable association.

UVM, ACC, and KICH are the cancer types where RPL32 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	All	0.834	0.433	<.001	111	view →
ACC	DFS	Median	All	0.247	0.623	<.001	104	view →
KICH	DFS	Tertile	III,IV	0.255	1.000	.003	84	view →
LIHC	OS	Median	III,IV	0.476	0.794	<.001	70	view →
LGG	DFS	Median	All	0.811	0.644	<.001	41	view →
SARC	DFS	Median	All	0.413	0.609	<.001	34	view →
MESO	DFS	Tertile	III,IV	0.671	0.118	.006	27	view →
THYM	OS	Tertile	II,III,IV	1.000	0.826	.007	26	view →
BLCA	DFS	Median	II,III,IV	0.562	0.456	.015	23	view →
PAAD	DFS	Quartile	All	0.377	0.586	.005	18	view →
OV	OS	Quartile	II,III,IV	0.258	0.361	.018	12	view →
DLBC	DFS	Median	All	1.000	0.668	.034	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

RPL32–UVM (OS)

Open the UVM breakdown →