RNU6-458P

Q-omics provides the consensus-scored RNU6-458P profile across patient tissues and cancer cell-line models. RNU6-458P expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in HNSC. Additionally, RNU6-458P RNA expression shows 1,232 significant gene co-expression associations, with the highest sampling consensus in STAD. Together, these results highlight HNSC, and STAD as cancer lineages where RNU6-458P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes RNU6-458P survival associations across molecular data types. RNU6-458P RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-458P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	HNSC (72)	view →

This table ranks reproducible RNU6-458P RNA expression–survival associations across cancer types. High RNU6-458P expression shows unfavorable associations in HNSC, BLCA, SKCM, ESCA and LGG. The HNSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify HNSC as the clearest survival context for RNU6-458P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.122	0.710	.001	72	view →
BLCA	DFS	Tertile	All	0.015	0.594	<.001	63	view →
SKCM	DFS	Tertile	All	0.058	0.757	<.001	27	view →
ESCA	DFS	Tertile	II,III,IV	0.082	0.523	<.001	18	view →
LGG	DFS	Tertile	All	0.089	0.845	<.001	18	view →

Pink = unfavorable, green = favorable. all 5 lineages →

RNU6-458P-HNSC (DFS)

Explore this curve interactively →