RPL28

Across TCGA patient cohorts, RPL28 mutation is significantly associated with the RNA expression of many other genes, with 424 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL28-associated genes across cancer lineages are RNU6-1274P, MIR8053, and MIR629. Each is linked with RPL28 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL28-to-partner and partner-to-RPL28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1274P grouped by RPL28-low versus RPL28-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL28→partner) and Y-score (partner→RPL28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RNU6-1274P →	+0.435	+5.925	.001	.002	3	2
LUAD	MIR8053 →	+0.421	+5.343	.001	.006	3	2
LUAD	MIR629 →	+0.506	+5.099	<.001	.008	3	2
LUAD	MRPL32P1 →	+0.229	+5.343	<.001	.006	3	2
LUSC	RNU6-662P →	+0.429	+5.706	<.001	.003	3	2
LUSC	MIR99A →	+0.520	+5.978	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 424 associations by consensus.

RNU6-1274P by RPL28 expression — READ

Explore this box plot interactively →