Q-omics provides the consensus-scored MIR99A profile across patient tissues and cancer cell-line models. MIR99A expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in HNSC. Additionally, MIR99A RNA expression shows 15,264 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight HNSC, and GBM as cancer lineages where MIR99A shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MIR99A survival associations across molecular data types. MIR99A RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MIR99A data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	8	HNSC (72)	view →

This table ranks reproducible MIR99A RNA expression–survival associations across cancer types. High MIR99A expression shows unfavorable associations in HNSC, SKCM, THCA, ACC and UCEC, but favorable associations in OV. The HNSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for MIR99A RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.059	0.712	<.001	72	view →
SKCM	DFS	Tertile	II,III,IV	0.164	0.685	<.001	33	view →
THCA	DFS	Tertile	IV	0.075	0.807	<.001	24	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
UCEC	OS	Tertile	IV	0.308	0.748	.009	18	view →
OV	OS	Tertile	All	0.922	0.833	.044	12	view →

Pink = unfavorable, green = favorable. all 8 lineages →

MIR99A-HNSC (OS)

Kaplan–Meier survival curve for MIR99A RNA expression in HNSC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MIR99A in patient tissues and cancer cell lines. In patient samples, MIR99A shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	15,264	GBM (4102)	view →
RNA	7,843	BRCA (2993)	view →
▼Mutation
RNA	15	UCEC (7)	view →