Across TCGA patient cohorts, MIR99A mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR99A-associated genes across cancer lineages are OR4M1, MIR299, and TUBB1P2. Each is linked with MIR99A in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR99A-to-partner and partner-to-MIR99A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR99A→partner) and Y-score (partner→MIR99A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR4M1 →	+0.121	+5.242	<.001	.007	3	1
COAD	MIR299 →	+0.339	+7.741	<.001	.009	3	1
COAD	TUBB1P2 →	+0.034	+7.741	<.001	.009	3	1
COAD	RNU1-41P →	+0.249	+7.741	<.001	.009	3	1
COAD	C2orf69P4 →	+0.084	+7.741	<.001	.009	3	1
UCEC	OR2AP1 →	+0.101	+5.852	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

MIR99A survival (RNA) · tumor vs normal (RNA) · all MIR99A data types