RPL23AP71

Across TCGA pan-cancer cohorts, RPL23AP71 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPL23AP71’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPL23AP71 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL23AP71 is over-expressed in tumor, although a few such as PAAD and THCA show the opposite, repressed pattern.

HNSC, PAAD, and LUSC are the cancer types where RPL23AP71 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL23AP71 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.073	.002	5	view →
PAAD	All	All	−0.157	.030	4	view →
LUSC	Male	II,III,IV	+0.049	.028	1	view →
THCA	All	All	−0.037	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPL23AP71–HNSC

Open the HNSC breakdown →