Q-omics provides the consensus-scored RPL23AP71 profile across patient tissues and cancer cell-line models. RPL23AP71 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, RPL23AP71 is differentially expressed in 4, with the highest sampling consensus in HNSC. Additionally, RPL23AP71 RNA expression shows 7,379 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KIRC, HNSC, and TGCT as cancer lineages where RPL23AP71 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPL23AP71 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPL23AP71 survival associations across molecular data types. RPL23AP71 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPL23AP71 RNA expression–survival associations across cancer types. High RPL23AP71 expression shows unfavorable associations in KIRC, CHOL, OV and THCA, but favorable associations in CESC and ESCA. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for RPL23AP71 RNA expression.
This table summarizes RPL23AP71 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for RPL23AP71. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPL23AP71 shows lower tumor expression in PAAD and THCA and higher tumor expression in HNSC and LUSC. The HNSC box plot shows higher RPL23AP71 RNA expression in tumor versus normal tissue (log2 FC = +0.073, t-test p = .002).
This table shows molecular features associated with RPL23AP71 in patient tissues and cancer cell lines. In patient samples, RPL23AP71 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
