RPL23AP7

Across TCGA patient cohorts, RPL23AP7 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL23AP7-associated genes across cancer lineages are RNU6-366P, RNU6-1228P, and MIR1251. Each is linked with RPL23AP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL23AP7-to-partner and partner-to-RPL23AP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-366P grouped by RPL23AP7-low versus RPL23AP7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL23AP7→partner) and Y-score (partner→RPL23AP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-366P →	+0.344	+4.226	<.001	.008	3	1
UCEC	RNU6-1228P →	+0.269	+5.049	.001	.002	3	1
UCEC	MIR1251 →	+0.342	+5.470	<.001	.001	3	1
UCEC	RN7SKP151 →	+0.255	+3.677	.007	.006	3	1
UCEC	HMGB1P12 →	+0.154	+3.993	.002	.001	3	1
UCEC	AP1B1P2 →	+0.307	+4.722	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

RNU6-366P by RPL23AP7 expression — UCEC

Explore this box plot interactively →