RPL14P1

Across TCGA patient cohorts, RPL14P1 mutation is significantly associated with the RNA expression of many other genes, with 104 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL14P1-associated genes across cancer lineages are GRAMD4P5, NMNAT1P5, and PLSCR5-AS1. Each is linked with RPL14P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL14P1-to-partner and partner-to-RPL14P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GRAMD4P5 grouped by RPL14P1-low versus RPL14P1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL14P1→partner) and Y-score (partner→RPL14P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GRAMD4P5 →	+0.065	+5.706	<.001	.003	3	2
SKCM	NMNAT1P5 →	+0.051	+4.038	<.001	<.001	3	2
UCEC	PLSCR5-AS1 →	+0.089	+4.137	.004	.008	3	2
SKCM	PPP1R2P2 →	+0.207	+3.197	<.001	.005	3	1
SKCM	BMI1P1 →	+0.035	+3.668	.003	.002	3	1
SKCM	LINC02632 →	+0.007	+4.665	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 104 associations by consensus.

GRAMD4P5 by RPL14P1 expression — LUSC

Explore this box plot interactively →