ribose 5-phosphate isomerase A pseudogene 1Genealiases: []
Q-omics provides the consensus-scored RPIAP1 profile across patient tissues and cancer cell-line models. RPIAP1 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in TGCT. Among the 18 cancer types available for tumor–normal comparison, RPIAP1 is differentially expressed in 3, with the highest sampling consensus in BLCA. Additionally, RPIAP1 RNA expression shows 5,855 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight TGCT, BLCA, and STAD as cancer lineages where RPIAP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPIAP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPIAP1 survival associations across molecular data types. RPIAP1 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPIAP1 RNA expression–survival associations across cancer types. High RPIAP1 expression shows unfavorable associations in TGCT, KICH, MESO, UCS, KIRP and ACC. The TGCT Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify TGCT as the clearest survival context for RPIAP1 RNA expression.
This table summarizes RPIAP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for RPIAP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPIAP1 shows lower tumor expression in KICH and higher tumor expression in BLCA and HNSC. The BLCA box plot shows higher RPIAP1 RNA expression in tumor versus normal tissue (log2 FC = +0.037, t-test p = .006).
This table shows molecular features associated with RPIAP1 in patient tissues and cancer cell lines. In patient samples, RPIAP1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
