RPH3AL

Across TCGA cell cohorts, RPH3AL RNA expression is significantly associated with the go_rna of many other GO terms, with 2,829 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible RPH3AL-associated GO terms across cancer lineages are Regulation of mitochondrion organization, ATP biosynthetic process, and AV node cell to bundle of His cell communication by electrical coupling. Each is linked with RPH3AL in more than 8 cancer types. Because this analysis shows association rather than direction, both RPH3AL-to-partner and partner-to-RPH3AL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrion organization grouped by RPH3AL-low versus RPH3AL-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPH3AL→partner) and Y-score (partner→RPH3AL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of mitochondrion organization →	+0.033	+0.770	.005	.002	3	9
BLOOD_Lymphoma	ATP biosynthetic process →	+0.080	+0.772	<.001	.006	3	7
LUNG_NSCLC_LUAD	AV node cell to bundle of His cell communication by electrical coupling →	-1.070	-1.227	<.001	.001	3	6
LUNG_NSCLC_LUSC	Regulation of protein secretion →	+0.103	+2.137	<.001	<.001	3	6
BONE	mRNA transcription →	+0.057	+0.916	.004	.002	3	6
BLOOD_Lymphoma	Proton motive force-driven ATP synthesis →	+0.079	+0.786	<.001	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,829 associations by consensus.

Regulation of mitochondrion organization by RPH3AL expression — CNS

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