RPGRIP1L

Across TCGA cell cohorts, RPGRIP1L RNA expression is significantly associated with the go_rna of many other GO terms, with 5,523 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPGRIP1L-associated GO terms across cancer lineages are Microtubule organizing center organization, Establishment of RNA localization, and Protein localization to cilium. Each is linked with RPGRIP1L in more than 16 cancer types. Because this analysis shows association rather than direction, both RPGRIP1L-to-partner and partner-to-RPGRIP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule organizing center organization grouped by RPGRIP1L-low versus RPGRIP1L-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPGRIP1L→partner) and Y-score (partner→RPGRIP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Microtubule organizing center organization →	+0.087	+0.983	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.088	+0.763	.001	.002	3	16
PANCREAS	Protein localization to cilium →	+0.070	+1.160	<.001	<.001	3	16
PANCREAS	Centrosome cycle →	+0.094	+0.983	<.001	<.001	3	16
URINARY_TRACT	Protein localization to ciliary transition zone →	+0.075	+0.786	<.001	<.001	3	16
BONE	Positive regulation of chromosome organization →	+0.089	+0.831	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,523 associations by consensus.

Microtubule organizing center organization by RPGRIP1L expression — PANCREAS

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