RP1

Across TCGA patient cohorts, RP1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,265 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RP1-associated genes across cancer lineages are FOXM1, BPIFB1, and MDH1B. Each is linked with RP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RP1-to-partner and partner-to-RP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RP1 versus FOXM1 in UCEC, with a Pearson correlation of -0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RP1→partner) and Y-score (partner→RP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXM1 →	-0.979	-1.295	<.001	.001	3	3
LSCC	BPIFB1 →	+2.977	+0.940	<.001	<.001	3	3
UCEC	MDH1B →	+2.267	+1.855	.007	.004	3	3
UCEC	SPATA4 →	+1.079	+1.295	<.001	.001	3	3
UCEC	RRAD →	+4.235	+1.935	.001	.002	3	3
UCEC	SH3BP1 →	-0.816	-1.935	.007	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,265 associations by consensus.

RP1 vs FOXM1 — UCEC

Explore this scatter interactively →