RP1

Across TCGA cell cohorts, RP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,469 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RP1-associated GO terms across cancer lineages are Regulation of extracellular matrix disassembly, Regulation of protein maturation, and Phototransduction, visible light. Each is linked with RP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both RP1-to-partner and partner-to-RP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of extracellular matrix disassembly grouped by RP1-low versus RP1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RP1→partner) and Y-score (partner→RP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of extracellular matrix disassembly →	+0.148	+1.039	<.001	<.001	3	10
KIDNEY	Regulation of protein maturation →	+0.165	+1.672	<.001	<.001	2	10
BONE	Phototransduction, visible light →	-0.269	-1.122	.001	.001	2	9
LUNG_NSCLC_LUSC	Oncogene-induced cell senescence →	+0.175	+0.882	<.001	<.001	3	8
PANCREAS	Positive regulation of protein processing →	+0.155	+0.753	<.001	.002	3	8
LUNG_NSCLC_LUAD	Regulation of cell-substrate junction assembly →	+0.051	+1.185	.003	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,469 associations by consensus.

Regulation of extracellular matrix disassembly by RP1 expression — PANCREAS

Explore this box plot interactively →