ROCR

Across TCGA patient cohorts, ROCR RNA expression is significantly associated with the protein abundance of many other proteins, with 12,863 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ROCR-associated proteins across cancer lineages are NFIX, SULT2B1_S318, and BBX_S844. Each is linked with ROCR in more than 2 cancer types. Because this analysis shows association rather than direction, both ROCR-to-partner and partner-to-ROCR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ROCR versus NFIX in BRCA, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ROCR→partner) and Y-score (partner→ROCR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NFIX →	+0.455	+1.262	<.001	<.001	3	3
BRCA	SULT2B1_S318 →	-0.836	-0.951	<.001	<.001	3	3
PDAC	BBX_S844 →	+0.254	+0.748	.001	.001	3	3
GBM	AFDN_S1275 →	+0.410	+0.305	.003	.007	3	3
PDAC	EEF2_S502 →	-0.889	-1.123	<.001	<.001	3	3
GBM	EHBP1L1 →	-0.370	-0.358	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,863 associations by consensus.

ROCR vs NFIX — BRCA

Explore this scatter interactively →