ROCR

Across TCGA pan-cancer cohorts, ROCR RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ROCR data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ROCR RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ROCR expression acts as an unfavorable survival marker, although some lineages such as ESCA and BRCA show a favorable association.

COAD, LUAD, and OV are the cancer types where ROCR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.321	0.545	.012	40	view →
LUAD	DFS	Tertile	IV	0.047	0.565	<.001	33	view →
OV	DFS	Median	IV	0.325	0.595	<.001	32	view →
ESCA	OS	Tertile	II,III,IV	0.693	0.353	.004	30	view →
BRCA	DFS	Tertile	All	0.635	0.455	.002	22	view →
UCEC	DFS	Tertile	All	0.551	0.678	<.001	22	view →
KIRP	OS	Quartile	All	0.806	0.930	.004	21	view →
LGG	DFS	Quartile	All	0.613	0.759	.008	18	view →
KIRC	DFS	Tertile	IV	0.217	0.465	.011	18	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
THYM	DFS	Median	All	0.504	0.941	.001	17	view →
MESO	DFS	Tertile	All	0.258	0.394	.044	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

ROCR–COAD (DFS)

Open the COAD breakdown →