ROCK1

Across TCGA patient cohorts, ROCK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,415 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ROCK1-associated proteins across cancer lineages are MRPS16, PPIF, and TMED9. Each is linked with ROCK1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ROCK1-to-partner and partner-to-ROCK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ROCK1 versus MRPS16 in OV, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ROCK1→partner) and Y-score (partner→ROCK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MRPS16 →	-0.359	-0.435	.001	.004	3	5
OV	PPIF →	-0.524	-0.567	.008	.007	3	5
PDAC	TMED9 →	-0.340	-0.349	<.001	<.001	3	4
OV	VAPB_S160 →	-0.956	-0.397	.006	.009	3	4
COAD	GRSF1 →	-0.400	-0.542	<.001	<.001	3	4
COAD	MRPS22 →	-0.316	-0.399	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,415 associations by consensus.

ROCK1 vs MRPS16 — OV

Explore this scatter interactively →