RNU7-75P

Across TCGA pan-cancer cohorts, RNU7-75P RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of RNU7-75P’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RNU7-75P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU7-75P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LUAD, LUSC, and BLCA are the cancer types where RNU7-75P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-75P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	+1.100	<.001	7	view →
LUSC	Male	II,III,IV	+1.355	<.001	6	view →
BLCA	All	All	+0.981	.002	6	view →
STAD	Male	All	+0.826	.001	6	view →
KIRC	Male	II,III,IV	+0.560	<.001	5	view →
HNSC	All	All	+0.374	.004	5	view →
CHOL	All	II,III,IV	+2.115	.028	4	view →
ESCA	Male	All	+1.292	<.001	4	view →
UCEC	All	III,IV	+0.743	.028	4	view →
COAD	All	II,III,IV	+0.414	.018	4	view →
THCA	Male	IV	−0.913	<.001	3	view →
LIHC	All	II,III,IV	+0.253	.034	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

RNU7-75P–LUAD

Open the LUAD breakdown →