Q-omics provides the consensus-scored RNU7-75P profile across patient tissues and cancer cell-line models. RNU7-75P expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, RNU7-75P is differentially expressed in 12, with the highest sampling consensus in LUAD. Additionally, RNU7-75P RNA expression shows 14,555 significant protein co-abundance associations, with the highest sampling consensus in HNSC. Together, these results highlight KIRP, LUAD, and HNSC as cancer lineages where RNU7-75P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU7-75P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU7-75P survival associations across molecular data types. RNU7-75P RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU7-75P RNA expression–survival associations across cancer types. High RNU7-75P expression shows unfavorable associations in KIRP, KIRC, SARC, UCEC and COAD, but favorable associations in READ. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify KIRP as the clearest survival context for RNU7-75P RNA expression.
This table summarizes RNU7-75P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in LUAD for RNA.
This table ranks reproducible tumor–normal expression differences for RNU7-75P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU7-75P shows higher tumor expression in LUAD, LUSC, BLCA, STAD, KIRC and HNSC. The LUAD box plot shows higher RNU7-75P RNA expression in tumor versus normal tissue (log2 FC = +1.100, t-test p < 0.001).
This table shows molecular features associated with RNU7-75P in patient tissues and cancer cell lines. In patient samples, RNU7-75P shows the broadest associations at the RNA and protein expression levels, with HNSC recurring as the lineage with the largest associated feature set.
