RNU7-45P

Across TCGA pan-cancer cohorts, RNU7-45P RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RNU7-45P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU7-45P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU7-45P expression acts as an unfavorable survival marker, although some lineages such as BLCA and HNSC show a favorable association.

KICH, BLCA, and LGG are the cancer types where RNU7-45P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Quartile	II,III,IV	0.708	1.000	<.001	54	view →
BLCA	DFS	Median	III,IV	0.342	0.220	.004	49	view →
LGG	OS	Quartile	All	0.296	0.505	<.001	28	view →
UCEC	DFS	Quartile	III,IV	0.686	0.818	.003	24	view →
HNSC	OS	Median	All	0.819	0.713	.004	20	view →
UVM	DFS	Tertile	III,IV	0.227	0.743	.036	18	view →
BRCA	DFS	Median	All	0.580	0.462	.006	17	view →
STAD	OS	Tertile	II,III,IV	0.768	0.650	.018	14	view →
ESCA	OS	Median	All	0.617	1.000	.009	12	view →
MESO	OS	Tertile	III,IV	0.646	0.417	.013	10	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	10	view →
COAD	DFS	Median	All	0.621	0.746	.029	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RNU7-45P–KICH (OS)

Open the KICH breakdown →