Q-omics provides the consensus-scored RNU7-45P profile across patient tissues and cancer cell-line models. RNU7-45P expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, RNU7-45P is differentially expressed in 6, with the highest sampling consensus in KICH. Additionally, RNU7-45P RNA expression shows 15,490 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KICH, and THYM as cancer lineages where RNU7-45P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU7-45P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU7-45P survival associations across molecular data types. RNU7-45P RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU7-45P RNA expression–survival associations across cancer types. High RNU7-45P expression shows unfavorable associations in KICH, LGG, UCEC and UVM, but favorable associations in BLCA and HNSC. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for RNU7-45P RNA expression.
This table summarizes RNU7-45P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for RNU7-45P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU7-45P shows lower tumor expression in KICH, BRCA, LUAD and LUSC and higher tumor expression in KIRC and CHOL. The KICH box plot shows higher RNU7-45P RNA expression in normal versus tumor tissue (log2 FC = −1.571, t-test p < 0.001).
This table shows molecular features associated with RNU7-45P in patient tissues and cancer cell lines. In patient samples, RNU7-45P shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
