RNU7-11P

Across TCGA pan-cancer cohorts, RNU7-11P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU7-11P’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNU7-11P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU7-11P is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

THCA, KIRC, and COAD are the cancer types where RNU7-11P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-11P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	III,IV	−0.466	.007	4	view →
KIRC	Female	All	+0.300	.020	3	view →
COAD	All	All	−0.126	.011	3	view →
LUSC	All	II,III,IV	−0.263	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU7-11P–THCA

Open the THCA breakdown →