RNU6-999P

Across TCGA patient cohorts, RNU6-999P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,132 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-999P-associated GO terms across cancer lineages are Negative regulation of stem cell differentiation, Regulation of microtubule cytoskeleton organization, and Regulation of microtubule-based process. Each is linked with RNU6-999P in more than 12 cancer types. Because this analysis shows association rather than direction, both RNU6-999P-to-partner and partner-to-RNU6-999P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of stem cell differentiation grouped by RNU6-999P-low versus RNU6-999P-high in COAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-999P→partner) and Y-score (partner→RNU6-999P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Negative regulation of stem cell differentiation →	+0.081	+0.113	<.001	.004	3	13
ESCA	Regulation of microtubule cytoskeleton organization →	+0.053	+0.342	<.001	<.001	3	12
UCEC	Regulation of microtubule-based process →	+0.051	+0.096	<.001	.006	2	13
COAD	Nucleotide-excision repair →	+0.048	+0.188	<.001	.001	3	12
UCEC	tRNA processing →	+0.052	+0.153	<.001	.003	2	13
ESCA	Autophagosome maturation →	+0.052	+0.343	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,132 associations by consensus.

Negative regulation of stem cell differentiation by RNU6-999P expression — COAD

Explore this box plot interactively →