RNU6-999P

Across TCGA pan-cancer cohorts, RNU6-999P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU6-999P data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher RNU6-999P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-999P expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

READ, LIHC, and KIRP are the cancer types where RNU6-999P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	All	0.360	0.828	<.001	108	view →
LIHC	OS	Tertile	II,III,IV	0.051	0.696	<.001	63	view →
KIRP	DFS	Tertile	All	0.197	0.622	<.001	48	view →
KIRC	DFS	Tertile	IV	0.127	0.630	.039	18	view →
ESCA	OS	Quartile	IV	0.127	0.597	.017	18	view →
CESC	DFS	Tertile	III,IV	0.240	0.726	.015	18	view →
LUSC	OS	Tertile	All	0.673	0.778	.018	12	view →
LUAD	DFS	Tertile	All	0.546	0.322	.030	12	view →
STAD	DFS	Tertile	IV	0.087	0.415	<.001	9	view →
ACC	DFS	Tertile	All	0.134	0.594	.029	9	view →
THCA	DFS	Tertile	III,IV	0.713	0.876	.031	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RNU6-999P–READ (DFS)

Open the READ breakdown →