RNU6-999P

Across TCGA pan-cancer cohorts, RNU6-999P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNU6-999P’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNU6-999P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-999P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA and BRCA are the cancer types where RNU6-999P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-999P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.109	.018	2	view →
BRCA	All	III,IV	+0.096	.039	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RNU6-999P–THCA

Open the THCA breakdown →