RNU6-90P

Across TCGA pan-cancer cohorts, RNU6-90P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RNU6-90P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU6-90P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-90P expression acts as an unfavorable survival marker, although some lineages such as BRCA and CESC show a favorable association.

KICH, BRCA, and OV are the cancer types where RNU6-90P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Quartile	II,III,IV	0.394	0.894	<.001	65	view →
BRCA	DFS	Quartile	III,IV	0.904	0.738	.002	37	view →
OV	OS	Median	All	0.281	0.356	.007	30	view →
COAD	OS	Tertile	IV	0.243	0.607	.014	26	view →
CESC	OS	Tertile	IV	0.897	0.374	.008	24	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	21	view →
READ	DFS	Tertile	IV	0.248	0.659	.016	18	view →
TGCT	OS	Tertile	II,III,IV	0.802	1.000	.040	18	view →
HNSC	DFS	Quartile	IV	0.242	0.516	.015	16	view →
MESO	OS	Median	III,IV	0.455	0.657	.013	16	view →
UVM	OS	Tertile	III,IV	0.231	0.836	.001	15	view →
SKCM	DFS	Quartile	III,IV	0.136	0.384	.006	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RNU6-90P–KICH (DFS)

Open the KICH breakdown →