RNU6-90P

Across TCGA pan-cancer cohorts, RNU6-90P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-90P’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where RNU6-90P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-90P is over-expressed in tumor, although a few such as READ and LUSC show the opposite, repressed pattern.

UCEC, READ, and LUSC are the cancer types where RNU6-90P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-90P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	+1.010	.021	2	view →
READ	All	All	−0.476	.005	2	view →
LUSC	All	All	−0.338	.011	2	view →
LIHC	Male	All	+0.209	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU6-90P–UCEC

Open the UCEC breakdown →