RNU6-886P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-886P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-886P data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher RNU6-886P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-886P expression acts as an unfavorable survival marker, although some lineages such as LGG and OV show a favorable association.

PAAD, COAD, and CHOL are the cancer types where RNU6-886P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PAADDFSTertileII,III,IV0.2270.455.00327view →
COADDFSTertileIV0.0280.496<.00118view →
CHOLOSTertileIII,IV0.2750.886.04518view →
LIHCOSTertileAll0.3930.716.00918view →
LGGOSTertileAll0.6710.388.00815view →
KIRCDFSTertileIV0.3490.672.02515view →
UCECDFSTertileAll0.8360.902.03812view →
BLCAOSTertileIV0.1350.314.0439view →
ACCDFSTertileIII,IV0.0500.380.0409view →
PCPGOSTertileAll0.7860.963<.0019view →
OVDFSTertileIII,IV0.6210.517.0426view →
LUADDFSTertileAll0.1750.389.0483view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration