RNU6-886P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-886P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU6-886P’s most consistent transcriptional readouts.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where RNU6-886P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-886P is over-expressed in tumor.

PRAD, LUAD, and BRCA are the cancer types where RNU6-886P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-886P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
PRADAllAll+0.271.0062view →
LUADAllAll+0.183.0321view →
BRCAAllII,III,IV+0.152.0431view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration