Across TCGA patient cohorts, RNU6-821P mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNU6-821P-associated genes across cancer lineages are RNU6-23P, RNU6-271P, and RNU6-1292P. Each is linked with RNU6-821P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU6-821P-to-partner and partner-to-RNU6-821P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-821P→partner) and Y-score (partner→RNU6-821P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-23P →	+0.737	+4.552	<.001	.005	3	1
UCEC	RNU6-271P →	+0.547	+4.852	<.001	.006	3	1
UCEC	RNU6-1292P →	+0.897	+5.453	<.001	.002	3	1
UCEC	TRGJP2 →	+1.074	+4.473	<.001	.005	3	1
UCEC	SLC25A51P1 →	+0.273	+4.661	<.001	.004	3	1
UCEC	MIR1284 →	+0.465	+4.551	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

RNU6-821P survival (RNA) · tumor vs normal (RNA) · all RNU6-821P data types