Q-omics provides the consensus-scored MIR1284 profile across patient tissues and cancer cell-line models. MIR1284 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in READ. Among the 18 cancer types available for tumor–normal comparison, MIR1284 is differentially expressed in 3, with the highest sampling consensus in THCA. Additionally, MIR1284 RNA expression shows 8,531 significant gene co-expression associations, with the highest sampling consensus in LAML. Together, these results highlight READ, THCA, and LAML as cancer lineages where MIR1284 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR1284 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR1284 survival associations across molecular data types. MIR1284 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR1284 RNA expression–survival associations across cancer types. High MIR1284 expression shows unfavorable associations in READ, LIHC, ACC, LUSC, HNSC and CHOL. The READ Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify READ as the clearest survival context for MIR1284 RNA expression.
This table summarizes MIR1284 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR1284. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR1284 shows lower tumor expression in THCA and KIRP and higher tumor expression in BLCA. The THCA box plot shows higher MIR1284 RNA expression in normal versus tumor tissue (log2 FC = −0.081, t-test p = .004).
This table shows molecular features associated with MIR1284 in patient tissues and cancer cell lines. In patient samples, MIR1284 shows the broadest associations at the RNA and protein expression levels, with LAML recurring as the lineage with the largest associated feature set.
