RNU6-665P

Across TCGA patient cohorts, RNU6-665P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,236 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-665P-associated GO terms across cancer lineages are Regulation of nuclear-transcribed mRNA poly(A) tail shortening, Regulation of cell cycle G1/S phase transition, and Neural nucleus development. Each is linked with RNU6-665P in more than 13 cancer types. Because this analysis shows association rather than direction, both RNU6-665P-to-partner and partner-to-RNU6-665P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nuclear-transcribed mRNA poly(A) tail shortening grouped by RNU6-665P-low versus RNU6-665P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-665P→partner) and Y-score (partner→RNU6-665P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of nuclear-transcribed mRNA poly(A) tail shortening →	+0.057	+0.641	<.001	<.001	3	14
ESCA	Regulation of cell cycle G1/S phase transition →	+0.043	+0.575	<.001	<.001	3	13
ESCA	Neural nucleus development →	+0.038	+0.620	<.001	<.001	3	13
STAD	Positive regulation of binding →	+0.041	+0.450	<.001	<.001	3	13
STAD	Protein modification by small protein removal →	+0.052	+0.480	<.001	<.001	3	13
STAD	Telencephalon development →	+0.035	+0.447	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,236 associations by consensus.

Regulation of nuclear-transcribed mRNA poly(A) tail shortening by RNU6-665P expression — ESCA

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