RNU6-665P

Across TCGA pan-cancer cohorts, RNU6-665P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-665P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-665P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-665P expression acts as an unfavorable survival marker, although some lineages such as LIHC and LUAD show a favorable association.

KIRC, LIHC, and CESC are the cancer types where RNU6-665P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Quartile	II,III,IV	0.396	0.595	<.001	76	view →
LIHC	OS	Tertile	II,III,IV	0.887	0.675	.006	57	view →
CESC	OS	Tertile	IV	0.117	0.617	<.001	36	view →
LUAD	DFS	Tertile	II,III,IV	0.848	0.656	.009	23	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	18	view →
UCS	DFS	Tertile	III,IV	0.107	0.454	.002	18	view →
LUSC	DFS	Quartile	III,IV	0.721	0.477	.019	7	view →
ESCA	OS	Median	III,IV	0.559	0.329	.023	6	view →
HNSC	DFS	Tertile	All	0.142	0.363	.035	3	view →
STAD	OS	Median	III,IV	0.688	0.550	.034	2	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU6-665P–KIRC (OS)

Open the KIRC breakdown →