RNU6-665P

Across TCGA pan-cancer cohorts, RNU6-665P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-665P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU6-665P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-665P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, THCA, and LIHC are the cancer types where RNU6-665P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-665P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.411	<.001	8	view →
THCA	Male	III,IV	−0.387	.018	2	view →
LIHC	Female	All	+0.192	.013	2	view →
LUSC	Female	III,IV	+0.730	.002	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU6-665P–KIRC

Open the KIRC breakdown →