RNU6-58P

Across TCGA patient cohorts, RNU6-58P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,527 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-58P-associated GO terms across cancer lineages are Positive regulation of protein localization to cilium, Appendage development, and Protein localization to cilium. Each is linked with RNU6-58P in more than 5 cancer types. Because this analysis shows association rather than direction, both RNU6-58P-to-partner and partner-to-RNU6-58P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to cilium grouped by RNU6-58P-low versus RNU6-58P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-58P→partner) and Y-score (partner→RNU6-58P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of protein localization to cilium →	+0.121	+0.190	<.001	.001	3	5
ESCA	Appendage development →	+0.120	+0.124	<.001	.001	3	5
ESCA	Protein localization to cilium →	+0.103	+0.236	<.001	.001	3	4
HNSC	DNA integration →	+0.065	+0.026	<.001	.006	1	6
UCEC	Peptidyl-lysine dimethylation →	+0.119	+0.059	<.001	.005	3	4
ESCA	Neural tube formation →	+0.156	+0.259	<.001	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,527 associations by consensus.

Positive regulation of protein localization to cilium by RNU6-58P expression — ESCA

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