Q-omics provides the consensus-scored RNU6-58P profile across patient tissues and cancer cell-line models. RNU6-58P expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in SKCM. Additionally, RNU6-58P RNA expression shows 6,550 significant gene co-expression associations, with the highest sampling consensus in UCEC. Together, these results highlight SKCM, and UCEC as cancer lineages where RNU6-58P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Premium analyses for RNU6-58P — synthetic lethality, tumor antigen, and pembrolizumab response.

View premium →

Survival associations

This table summarizes RNU6-58P survival associations across molecular data types. RNU6-58P RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-58P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	7	SKCM (54)	view →

This table ranks reproducible RNU6-58P RNA expression–survival associations across cancer types. High RNU6-58P expression shows unfavorable associations in SKCM, STAD, KIRC, UCEC and TGCT, but favorable associations in GBM. The SKCM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for RNU6-58P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.044	0.738	<.001	54	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	45	view →
KIRC	DFS	Tertile	IV	0.127	0.619	.008	36	view →
UCEC	OS	Tertile	All	0.754	0.928	.001	36	view →
GBM	DFS	Tertile	All	1.000	0.194	.008	24	view →
TGCT	DFS	Tertile	All	0.081	0.673	.035	18	view →

Pink = unfavorable, green = favorable. all 7 lineages →

RNU6-58P-SKCM (DFS)

Kaplan–Meier survival curve for RNU6-58P RNA expression in SKCM: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU6-58P in patient tissues and cancer cell lines. In patient samples, RNU6-58P shows the broadest associations at the RNA and protein expression levels, with UCEC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	6,550	UCEC (2695)	view →
Function (RNA)	5,527	STAD (5218)	view →