RNU6-58P

Across TCGA pan-cancer cohorts, RNU6-58P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-58P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU6-58P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-58P expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

SKCM, STAD, and KIRC are the cancer types where RNU6-58P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.044	0.738	<.001	54	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	45	view →
KIRC	DFS	Tertile	IV	0.127	0.619	.008	36	view →
UCEC	OS	Tertile	All	0.754	0.928	.001	36	view →
GBM	DFS	Tertile	All	1.000	0.194	.008	24	view →
TGCT	DFS	Tertile	All	0.081	0.673	.035	18	view →
SARC	DFS	Tertile	All	0.222	0.522	.023	18	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RNU6-58P–SKCM (DFS)

Open the SKCM breakdown →