RNU6-583P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-583P RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RNU6-583P data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RNU6-583P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-583P expression acts as an unfavorable survival marker, although some lineages such as COAD and UCS show a favorable association.

LIHC, LUAD, and LGG are the cancer types where RNU6-583P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCOSTertileAll0.6710.800.00555view →
LUADDFSQuartileIII,IV0.5040.680.01345view →
LGGOSMedianAll0.7190.868<.00142view →
CESCDFSTertileIII,IV0.5350.858.00340view →
KICHDFSTertileAll0.4440.919.00326view →
COADOSMedianII,III,IV0.7820.470.00525view →
UCSDFSMedianIV0.9520.367.00124view →
BLCAOSTertileIII,IV0.7100.559.00423view →
CHOLOSMedianIII,IV0.2861.000.00821view →
KIRCDFSTertileAll0.5510.696.01919view →
SARCDFSMedianAll0.4220.581.00219view →
PCPGDFSTertileAll0.2310.830.00818view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

RNU6-583P–LIHC (OS)

Kaplan–Meier survival curve for RNU6-583P RNA-high vs -low samples in LIHC.

Open the LIHC breakdown →

Exploration