RNA, U6 small nuclear 583, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU6-583P profile across patient tissues and cancer cell-line models. RNU6-583P expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in LIHC. Among the 18 cancer types available for tumor–normal comparison, RNU6-583P is differentially expressed in 11, with the highest sampling consensus in LUSC. Additionally, RNU6-583P RNA expression shows 13,708 significant gene co-expression associations, with the highest sampling consensus in DLBC. Together, these results highlight LIHC, LUSC, and DLBC as cancer lineages where RNU6-583P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU6-583P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU6-583P survival associations across molecular data types. RNU6-583P RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU6-583P RNA expression–survival associations across cancer types. High RNU6-583P expression shows unfavorable associations in LIHC, LUAD, LGG, CESC and KICH, but favorable associations in COAD. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .005). Together, the overview and detailed table identify LIHC as the clearest survival context for RNU6-583P RNA expression.
This table summarizes RNU6-583P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for RNU6-583P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-583P shows higher tumor expression in LUSC, UCEC, BRCA, LUAD, BLCA and STAD. The LUSC box plot shows higher RNU6-583P RNA expression in tumor versus normal tissue (log2 FC = +1.530, t-test p < 0.001).
This table shows molecular features associated with RNU6-583P in patient tissues and cancer cell lines. In patient samples, RNU6-583P shows the broadest associations at the RNA and protein expression levels, with DLBC recurring as the lineage with the largest associated feature set.
