RNU6-581P

Across TCGA patient cohorts, RNU6-581P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,507 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-581P-associated GO terms across cancer lineages are Positive regulation of stem cell population maintenance, Neuron projection organization, and Positive regulation of protein modification by small protein conjugation or removal. Each is linked with RNU6-581P in more than 6 cancer types. Because this analysis shows association rather than direction, both RNU6-581P-to-partner and partner-to-RNU6-581P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stem cell population maintenance grouped by RNU6-581P-low versus RNU6-581P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-581P→partner) and Y-score (partner→RNU6-581P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of stem cell population maintenance →	+0.114	+0.232	<.001	<.001	3	7
ESCA	Neuron projection organization →	+0.071	+0.138	<.001	<.001	3	6
ESCA	Positive regulation of protein modification by small protein conjugation or removal →	+0.109	+0.163	<.001	.002	3	6
ESCA	Regulation of ubiquitin-dependent protein catabolic process →	+0.100	+0.202	<.001	.002	3	6
ESCA	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.096	+0.150	<.001	.004	2	7
ESCA	Positive regulation of intrinsic apoptotic signaling pathway →	+0.099	+0.145	<.001	.007	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,507 associations by consensus.

Positive regulation of stem cell population maintenance by RNU6-581P expression — ESCA

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