RNU6-581P

Across TCGA pan-cancer cohorts, RNU6-581P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-581P data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher RNU6-581P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU6-581P expression acts as an unfavorable survival marker, although some lineages such as OV and ESCA show a favorable association.

OV, LUSC, and STAD are the cancer types where RNU6-581P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Tertile	All	0.909	0.676	.003	84	view →
LUSC	OS	Tertile	II,III,IV	0.133	0.732	<.001	54	view →
STAD	OS	Tertile	All	0.258	0.748	<.001	45	view →
PAAD	DFS	Tertile	All	0.079	0.468	<.001	18	view →
HNSC	DFS	Tertile	II,III,IV	0.262	0.665	.021	18	view →
CHOL	DFS	Tertile	All	0.074	0.436	.034	9	view →
ESCA	DFS	Tertile	II,III,IV	0.630	0.296	.043	9	view →
LGG	OS	Tertile	All	0.800	0.915	.042	6	view →
KIRC	DFS	Tertile	All	0.667	0.869	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RNU6-581P–OV (OS)

Open the OV breakdown →