RNU6-538P

Across TCGA patient cohorts, RNU6-538P RNA expression is significantly associated with the go_rna of many other GO terms, with 3,284 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-538P-associated GO terms across cancer lineages are Programmed cell death in response to reactive oxygen species, Modification of synaptic structure, and Regulation of helicase activity. Each is linked with RNU6-538P in more than 2 cancer types. Because this analysis shows association rather than direction, both RNU6-538P-to-partner and partner-to-RNU6-538P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Programmed cell death in response to reactive oxygen species grouped by RNU6-538P-low versus RNU6-538P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-538P→partner) and Y-score (partner→RNU6-538P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Programmed cell death in response to reactive oxygen species →	+0.135	+0.054	<.001	<.001	3	2
STAD	Modification of synaptic structure →	+0.171	+0.053	<.001	.001	3	2
STAD	Regulation of helicase activity →	+0.148	+0.093	<.001	.003	3	2
STAD	Establishment of centrosome localization →	+0.145	+0.049	<.001	.002	3	2
STAD	Long-term synaptic potentiation →	+0.052	+0.075	<.001	.003	3	2
STAD	Regulation of lysosome size →	+0.114	+0.073	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,284 associations by consensus.

Programmed cell death in response to reactive oxygen species by RNU6-538P expression — STAD

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