Q-omics provides the consensus-scored RNU6-538P profile across patient tissues and cancer cell-line models. RNU6-538P expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in LUSC. Additionally, RNU6-538P RNA expression shows 3,284 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight LUSC, and STAD as cancer lineages where RNU6-538P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU6-538P survival associations across molecular data types. RNU6-538P RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-538P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	LUSC (63)	view →

This table ranks reproducible RNU6-538P RNA expression–survival associations across cancer types. High RNU6-538P expression shows unfavorable associations in LUSC, KIRC, ACC, LAML and STAD, but favorable associations in ESCA. The LUSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LUSC as the clearest survival context for RNU6-538P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	III,IV	0.079	0.658	<.001	63	view →
KIRC	OS	Tertile	II,III,IV	0.168	0.696	.021	54	view →
ACC	OS	Tertile	All	0.133	0.686	.004	54	view →
LAML	DFS	Tertile	All	0.028	0.572	<.001	36	view →
STAD	OS	Tertile	All	0.247	0.735	.001	36	view →
ESCA	DFS	Tertile	III,IV	0.769	0.291	.034	18	view →

Pink = unfavorable, green = favorable. all 6 lineages →

RNU6-538P-LUSC (DFS)

Kaplan–Meier survival curve for RNU6-538P RNA expression in LUSC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU6-538P in patient tissues and cancer cell lines. In patient samples, RNU6-538P shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	3,284	STAD (3270)	view →
RNA	2,796	STAD (1993)	view →