RNU6-498P

Across TCGA patient cohorts, RNU6-498P RNA expression is significantly associated with the mutation status of many other genes, with 37 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RNU6-498P-associated genes across cancer lineages are MYH9, GRAP2, and ASF1B. Each is linked with RNU6-498P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU6-498P-to-partner and partner-to-RNU6-498P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH9 grouped by RNU6-498P-low versus RNU6-498P-high in BRCA.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-498P→partner) and Y-score (partner→RNU6-498P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MYH9 →	+4.531	+0.028	.003	<.001	3	1
BRCA	GRAP2 →	+8.055	+0.368	.007	<.001	3	1
BRCA	ASF1B →	+8.055	+0.203	.007	<.001	3	1
BRCA	VWF →	+5.354	+0.069	.001	<.001	3	1
BRCA	OR12D3 →	+8.055	+0.368	.007	<.001	3	1
BRCA	PACRG →	+8.055	+0.203	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

MYH9 by RNU6-498P expression — BRCA

Explore this box plot interactively →