Q-omics provides the consensus-scored RNU6-498P profile across patient tissues and cancer cell-line models. RNU6-498P expression is associated with patient survival in 4 of 34 cancer types, with the highest sampling consensus in SKCM. Additionally, RNU6-498P RNA expression shows 82 significant gene co-expression associations, with the highest sampling consensus in LAML. Together, these results highlight SKCM, and LAML as cancer lineages where RNU6-498P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Premium analyses for RNU6-498P — synthetic lethality, tumor antigen, and pembrolizumab response.

View premium →

Survival associations

This table summarizes RNU6-498P survival associations across molecular data types. RNU6-498P RNA expression shows survival associations in the most cancer types (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-498P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	4	SKCM (117)	view →

This table ranks reproducible RNU6-498P RNA expression–survival associations across cancer types. High RNU6-498P expression shows unfavorable associations in SKCM, ESCA, LAML and PRAD. The SKCM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for RNU6-498P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.048	0.738	<.001	117	view →
ESCA	DFS	Tertile	All	0.075	0.533	<.001	36	view →
LAML	DFS	Tertile	All	0.202	0.581	.006	36	view →
PRAD	DFS	Tertile	All	0.600	0.936	<.001	18	view →

Pink = unfavorable, green = favorable. all 4 lineages →

RNU6-498P-SKCM (DFS)

Kaplan–Meier survival curve for RNU6-498P RNA expression in SKCM: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU6-498P in patient tissues and cancer cell lines. In patient samples, RNU6-498P shows the broadest associations at the RNA and protein expression levels, with LAML recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	82	LAML (38)	view →
Mutation	37	BRCA (37)	view →